Alopecia areata, also known as spot baldness, is a condition in which hair is lost from some or all areas of the body. Often it results in a few bald spots on the scalp, each about the size of a coin. The disease may cause psychological stress. People are generally otherwise healthy. In a few cases, all the hair on the scalp is lost (alopecia totalis) or all body hair is lost (alopecia universalis) and loss can be permanent.
Alopecia areata 是一种免疫系统攻击毛囊的疾病,导致暂时性脱发且不留疤痕。它可表现为局部斑片脱发,也可累及整个头皮或全身,约有 2% 的人在其一生中的某个阶段会受到影响。其根本原因似乎是毛囊周围自然保护屏障的破坏。 Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata(斑秃)是一种免疫系统攻击毛囊的疾病,导致头皮和身体其他多毛部位脱发。它影响全世界约有 2% 的人。虽然可以发生在任何年龄,但儿童的发病率为 1.92%,而成人为 1.47%,儿童比成人更常见。女性,尤其是 50 岁以上的女性,往往比男性更易患此病。将皮质类固醇直接注射到受影响的区域比局部涂抹效果更好。 Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
斑秃被认为是一种与毛囊免疫系统相关的自身免疫性疾病。其潜在机制涉及机体无法识别自身细胞,进而导致免疫介导的毛囊破坏。
○ 治疗 - 非处方药
轻度斑秃患者有时可在一年内自行恢复,无需治疗。但多数患者会在头皮的其他部位出现复发。
#Hydrocortisone cream
○ 治疗
病灶内注射类固醇是最有效的治疗方法。如果大面积头皮受到影响,可以尝试免疫疗法。
#Triamcinolone intralesional injection
#DPCP immunotherapy